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Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis

Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense, and is a major cause of systemic and neurological disability throughout sub-Saharan Africa. Following early-stage disease, the trypanosomes cross...

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Detalhes bibliográficos
Main Authors: Rodgers, Jean, Stone, Trevor W., Barrett, Michael P., Bradley, Barbara, Kennedy, Peter G. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677800/
https://ncbi.nlm.nih.gov/pubmed/19339256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp074
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