Kynurenine Pathway Activation in Human African Trypanosomiasis

BACKGROUND. The kynurenine pathway of tryptophan oxidation is associated with central nervous system (CNS) inflammatory pathways. Inhibition of this pathway ameliorates CNS inflammation in rodent models of the late (meningoencephalitic) stage of human African trypanosomiasis (HAT). In this study, we...

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Dades bibliogràfiques
Publicat a:J Infect Dis
Autors principals: Sternberg, Jeremy M., Forrest, Caroline M., Dalton, R. Neil, Turner, Charles, Rodgers, Jean, Stone, Trevor W., Kennedy, Peter G. E.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Major Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388295/
https://ncbi.nlm.nih.gov/pubmed/28013248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw623
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