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PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation

Mitophagy is a highly specialized process to remove dysfunctional or superfluous mitochondria through the macroautophagy/autophagy pathway, aimed at protecting cells from the damage of disordered mitochondrial metabolism and apoptosis induction. PINK1, a neuroprotective protein mutated in autosomal...

詳細記述

保存先:
書誌詳細
出版年:Autophagy
主要な著者: Gelmetti, Vania, De Rosa, Priscilla, Torosantucci, Liliana, Marini, Elettra Sara, Romagnoli, Alessandra, Di Rienzo, Martina, Arena, Giuseppe, Vignone, Domenico, Fimia, Gian Maria, Valente, Enza Maria
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388214/
https://ncbi.nlm.nih.gov/pubmed/28368777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1277309
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