Absence of physiological Ca(2+) transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation

BACKGROUND: Motor neurons control muscle contraction by initiating action potentials in muscle. Denervation of muscle from motor neurons leads to muscle atrophy, which is linked to mitochondrial dysfunction. It is known that denervation promotes mitochondrial reactive oxygen species (ROS) production...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Skelet Muscle
Auteurs principaux: Karam, Chehade, Yi, Jianxun, Xiao, Yajuan, Dhakal, Kamal, Zhang, Lin, Li, Xuejun, Manno, Carlo, Xu, Jiejia, Li, Kaitao, Cheng, Heping, Ma, Jianjie, Zhou, Jingsong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387329/
https://ncbi.nlm.nih.gov/pubmed/28395670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-017-0123-0
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires