Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer

Cystatin SN (CST1) is a specific inhibitor belonging to the cystatin superfamily that controls the proteolytic activities of cysteine proteases such as cathepsins. Our previous study showed that high CST1 expression enhances tumor metastasis and invasiveness in colorectal cancer. Recently, auranofin...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Oh, Byung Moo, Lee, Seon-Jin, Cho, Hee Jun, Park, Yun Sun, Kim, Jong-Tae, Yoon, Suk Ran, Lee, Sang Chul, Lim, Jong-Seok, Kim, Bo-Yeon, Choe, Yong-Kyung, Lee, Hee Gu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386512/
https://ncbi.nlm.nih.gov/pubmed/28300829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.100
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