Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer

Cystatin SN (CST1) is a specific inhibitor belonging to the cystatin superfamily that controls the proteolytic activities of cysteine proteases such as cathepsins. Our previous study showed that high CST1 expression enhances tumor metastasis and invasiveness in colorectal cancer. Recently, auranofin...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Oh, Byung Moo, Lee, Seon-Jin, Cho, Hee Jun, Park, Yun Sun, Kim, Jong-Tae, Yoon, Suk Ran, Lee, Sang Chul, Lim, Jong-Seok, Kim, Bo-Yeon, Choe, Yong-Kyung, Lee, Hee Gu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386512/
https://ncbi.nlm.nih.gov/pubmed/28300829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.100
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