Cystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity

Cystatin SN (CST1) is one of the several salivary cystatins that form tight equimolar complexes with cysteine proteases, such as the cathepsins. High expression of CST1 is correlated with advanced pTNM stage in gastric cancer. However, the functional role of CST1 in tumorigenesis has not been elucid...

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Detalhes bibliográficos
Main Authors: Kim, J-T, Lee, S-J, Kang, M A, Park, J E, Kim, B-Y, Yoon, D-Y, Yang, Y, Lee, C-H, Yeom, Y I, Choe, Y-K, Lee, H G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877556/
https://ncbi.nlm.nih.gov/pubmed/24357805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.485
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