Extracellular cystatin SN and cathepsin B prevent cellular senescence by inhibiting abnormal glycogen accumulation

Cystatin SN (CST1), a known inhibitor of cathepsin B (CatB), has important roles in tumor development. Paradoxically, CatB is a member of the cysteine cathepsin family that acts in cellular processes, such as tumor development and invasion. However, the relationship between CST1 and CatB, and their...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Oh, Sang-Seok, Park, Soojong, Lee, Ki-Won, Madhi, Hamadi, Park, Sae Gwang, Lee, Hee Gu, Cho, Yong-Yeon, Yoo, Jiyun, Dong Kim, Kwang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477579/
https://ncbi.nlm.nih.gov/pubmed/28383558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.153
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