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Asymmetric Copper Hydride-Catalyzed Markovnikov Hydrosilylation of Vinylarenes and Vinyl Heterocycles

[Image: see text] We report a highly enantioselective CuH-catalyzed Markovnikov hydrosilylation of vinylarenes and vinyl heterocycles. This method has a broad scope and enables both the synthesis of isolable silanes and the conversion of crude products to chiral alcohols. Density functional theory c...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Gribble, Michael W., Pirnot, Michael T., Bandar, Jeffrey S., Liu, Richard Y., Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386394/
https://ncbi.nlm.nih.gov/pubmed/28117996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b13029
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