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Mechanistic Studies Lead to Dramatically Improved Reaction Conditions for the Cu-Catalyzed Asymmetric Hydroamination of Olefins

[Image: see text] Enantioselective copper(I) hydride (CuH)-catalyzed hydroamination has undergone significant development over the past several years. To gain a general understanding of the factors governing these reactions, kinetic and spectroscopic studies were performed on the CuH-catalyzed hydro...

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Publicado en:J Am Chem Soc
Autores principales: Bandar, Jeffrey S., Pirnot, Michael T., Buchwald, Stephen L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2015
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768687/
https://ncbi.nlm.nih.gov/pubmed/26522837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b10219
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