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Variable Surface Epitopes in the Crystal Structure of Dengue Virus Type 3 Envelope Glycoprotein

Dengue virus is an emerging global health threat. The major envelope glycoprotein, E, mediates viral attachment and entry by membrane fusion. Antibodies that bind but fail to neutralize noncognate serotypes enhance infection. We have determined the crystal structure of a soluble fragment of the enve...

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Hlavní autoři: Modis, Yorgo, Ogata, Steven, Clements, David, Harrison, Stephen C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC538574/
https://ncbi.nlm.nih.gov/pubmed/15613349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1223-1231.2005
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