Crystal Structure of West Nile Virus Envelope Glycoprotein Reveals Viral Surface Epitopes

West Nile virus, a member of the Flavivirus genus, causes fever that can progress to life-threatening encephalitis. The major envelope glycoprotein, E, of these viruses mediates viral attachment and entry by membrane fusion. We have determined the crystal structure of a soluble fragment of West Nile...

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Bibliografische gegevens
Hoofdauteurs: Kanai, Ryuta, Kar, Kalipada, Anthony, Karen, Gould, L. Hannah, Ledizet, Michel, Fikrig, Erol, Marasco, Wayne A., Koski, Raymond A., Modis, Yorgo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2006
Onderwerpen:
Structure and Assembly
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1642136/
https://ncbi.nlm.nih.gov/pubmed/16943291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01735-06
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