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A ligand-binding pocket in the dengue virus envelope glycoprotein

Dengue virus is an emerging global health threat. Its major envelope glycoprotein, E, mediates viral attachment and entry by membrane fusion. A crystal structure of the soluble ectodomain of E from dengue virus type 2 reveals a hydrophobic pocket lined by residues that influence the pH threshold for...

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Autores principales: Modis, Yorgo, Ogata, Steven, Clements, David, Harrison, Stephen C.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC165817/
https://ncbi.nlm.nih.gov/pubmed/12759475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0832193100
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