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A ligand-binding pocket in the dengue virus envelope glycoprotein

Dengue virus is an emerging global health threat. Its major envelope glycoprotein, E, mediates viral attachment and entry by membrane fusion. A crystal structure of the soluble ectodomain of E from dengue virus type 2 reveals a hydrophobic pocket lined by residues that influence the pH threshold for...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Modis, Yorgo, Ogata, Steven, Clements, David, Harrison, Stephen C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165817/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12759475/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0832193100
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