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Crystal Structure of Dengue Virus Type 1 Envelope Protein in the Postfusion Conformation and Its Implications for Membrane Fusion

Dengue virus relies on a conformational change in its envelope protein, E, to fuse the viral lipid membrane with the endosomal membrane and thereby deliver the viral genome into the cytosol. We have determined the crystal structure of a soluble fragment E (sE) of dengue virus type 1 (DEN-1). The pro...

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Main Authors: Nayak, Vinod, Dessau, Moshe, Kucera, Kaury, Anthony, Karen, Ledizet, Michel, Modis, Yorgo
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668458/
https://ncbi.nlm.nih.gov/pubmed/19244332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02574-08
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