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Crystal Structure of Dengue Virus Type 1 Envelope Protein in the Postfusion Conformation and Its Implications for Membrane Fusion

Dengue virus relies on a conformational change in its envelope protein, E, to fuse the viral lipid membrane with the endosomal membrane and thereby deliver the viral genome into the cytosol. We have determined the crystal structure of a soluble fragment E (sE) of dengue virus type 1 (DEN-1). The pro...

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Hlavní autoři: Nayak, Vinod, Dessau, Moshe, Kucera, Kaury, Anthony, Karen, Ledizet, Michel, Modis, Yorgo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668458/
https://ncbi.nlm.nih.gov/pubmed/19244332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02574-08
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