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Variable Surface Epitopes in the Crystal Structure of Dengue Virus Type 3 Envelope Glycoprotein

Dengue virus is an emerging global health threat. The major envelope glycoprotein, E, mediates viral attachment and entry by membrane fusion. Antibodies that bind but fail to neutralize noncognate serotypes enhance infection. We have determined the crystal structure of a soluble fragment of the enve...

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Autors principals: Modis, Yorgo, Ogata, Steven, Clements, David, Harrison, Stephen C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC538574/
https://ncbi.nlm.nih.gov/pubmed/15613349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1223-1231.2005
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