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Quantification of the Effects on Viral DNA Synthesis of Reverse Transcriptase Mutations Conferring Human Immunodeficiency Virus Type 1 Resistance to Nucleoside Analogues

Human immunodeficiency virus type I (HIV-1) reverse transcriptase (RT) resistance mutations reduce the susceptibility of the virus to nucleoside analogues but may also impair viral DNA synthesis. To further characterize the effect of nucleoside analogue resistance mutations on the efficiency and kin...

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Библиографические подробности
Главные авторы: Bouchonnet, Francine, Dam, Elisabeth, Mammano, Fabrizio, de Soultrait, Vaea, Henneré, Gaëlle, Benech, Henri, Clavel, François, Hance, Allan J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC538537/
https://ncbi.nlm.nih.gov/pubmed/15613309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.812-822.2005
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