Quantification of the Effects on Viral DNA Synthesis of Reverse Transcriptase Mutations Conferring Human Immunodeficiency Virus Type 1 Resistance to Nucleoside Analogues

Human immunodeficiency virus type I (HIV-1) reverse transcriptase (RT) resistance mutations reduce the susceptibility of the virus to nucleoside analogues but may also impair viral DNA synthesis. To further characterize the effect of nucleoside analogue resistance mutations on the efficiency and kin...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Bouchonnet, Francine, Dam, Elisabeth, Mammano, Fabrizio, de Soultrait, Vaea, Henneré, Gaëlle, Benech, Henri, Clavel, François, Hance, Allan J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2005
Fag:	Vaccines and Antiviral Agents
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538537/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15613309/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.2.812-822.2005
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