Quantification of the Effects on Viral DNA Synthesis of Reverse Transcriptase Mutations Conferring Human Immunodeficiency Virus Type 1 Resistance to Nucleoside Analogues

Human immunodeficiency virus type I (HIV-1) reverse transcriptase (RT) resistance mutations reduce the susceptibility of the virus to nucleoside analogues but may also impair viral DNA synthesis. To further characterize the effect of nucleoside analogue resistance mutations on the efficiency and kin...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Bouchonnet, Francine, Dam, Elisabeth, Mammano, Fabrizio, de Soultrait, Vaea, Henneré, Gaëlle, Benech, Henri, Clavel, François, Hance, Allan J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2005
Schlagworte:	Vaccines and Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538537/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15613309/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.2.812-822.2005
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