Quantification of the Effects on Viral DNA Synthesis of Reverse Transcriptase Mutations Conferring Human Immunodeficiency Virus Type 1 Resistance to Nucleoside Analogues

Human immunodeficiency virus type I (HIV-1) reverse transcriptase (RT) resistance mutations reduce the susceptibility of the virus to nucleoside analogues but may also impair viral DNA synthesis. To further characterize the effect of nucleoside analogue resistance mutations on the efficiency and kin...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Bouchonnet, Francine, Dam, Elisabeth, Mammano, Fabrizio, de Soultrait, Vaea, Henneré, Gaëlle, Benech, Henri, Clavel, François, Hance, Allan J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2005
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538537/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15613309/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.2.812-822.2005
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