Quantification of the Effects on Viral DNA Synthesis of Reverse Transcriptase Mutations Conferring Human Immunodeficiency Virus Type 1 Resistance to Nucleoside Analogues

Human immunodeficiency virus type I (HIV-1) reverse transcriptase (RT) resistance mutations reduce the susceptibility of the virus to nucleoside analogues but may also impair viral DNA synthesis. To further characterize the effect of nucleoside analogue resistance mutations on the efficiency and kin...

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Dettagli Bibliografici

Pubblicato in:	J Virol
Autori principali:	Bouchonnet, Francine, Dam, Elisabeth, Mammano, Fabrizio, de Soultrait, Vaea, Henneré, Gaëlle, Benech, Henri, Clavel, François, Hance, Allan J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2005
Soggetti:	Vaccines and Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538537/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15613309/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.2.812-822.2005
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