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The p53 family members have distinct roles during mammalian embryonic development

The p53 tumor suppressor is a member of a multi-protein family, including the p63 and p73 transcription factors. These proteins can bind to the same consensus sites in DNA and activate the same target genes, suggesting that there could be functional redundancy between them. Indeed, double mutant mic...

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Dades bibliogràfiques
Publicat a:Cell Death Differ
Autors principals: Van Nostrand, Jeanine L, Bowen, Margot E, Vogel, Hannes, Barna, Maria, Attardi, Laura D
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384018/
https://ncbi.nlm.nih.gov/pubmed/28211873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.128
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