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The p53 family members have distinct roles during mammalian embryonic development

The p53 tumor suppressor is a member of a multi-protein family, including the p63 and p73 transcription factors. These proteins can bind to the same consensus sites in DNA and activate the same target genes, suggesting that there could be functional redundancy between them. Indeed, double mutant mic...

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Библиографические подробности
Опубликовано в: :Cell Death Differ
Главные авторы: Van Nostrand, Jeanine L, Bowen, Margot E, Vogel, Hannes, Barna, Maria, Attardi, Laura D
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384018/
https://ncbi.nlm.nih.gov/pubmed/28211873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.128
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