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Members of the S100 family bind p53 in two distinct ways

p53 binds to some members of the S100 family (S100B, S100A4, S100A2, and S100A1). We previously showed that both S100B and S100A4 bind to the p53 tetramerization domain, and consequently control its oligomerization state, but only S100B binds to the C-terminal negative regulatory domain (NRD). Here,...

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Detalhes bibliográficos
Main Authors: Fernandez-Fernandez, Maria Rosario, Rutherford, Trevor J., Fersht, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548378/
https://ncbi.nlm.nih.gov/pubmed/18694925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.035527.108
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