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The p53 family members have distinct roles during mammalian embryonic development

The p53 tumor suppressor is a member of a multi-protein family, including the p63 and p73 transcription factors. These proteins can bind to the same consensus sites in DNA and activate the same target genes, suggesting that there could be functional redundancy between them. Indeed, double mutant mic...

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Bibliografiska uppgifter
I publikationen:Cell Death Differ
Huvudupphovsmän: Van Nostrand, Jeanine L, Bowen, Margot E, Vogel, Hannes, Barna, Maria, Attardi, Laura D
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384018/
https://ncbi.nlm.nih.gov/pubmed/28211873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.128
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