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The p53 family members have distinct roles during mammalian embryonic development

The p53 tumor suppressor is a member of a multi-protein family, including the p63 and p73 transcription factors. These proteins can bind to the same consensus sites in DNA and activate the same target genes, suggesting that there could be functional redundancy between them. Indeed, double mutant mic...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Van Nostrand, Jeanine L, Bowen, Margot E, Vogel, Hannes, Barna, Maria, Attardi, Laura D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384018/
https://ncbi.nlm.nih.gov/pubmed/28211873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.128
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