Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection

Recombinant, Escherichia coli-derived outer membrane vesicles (rOMVs), which display heterologous protein subunits, have potential as a vaccine adjuvant platform. One drawback to rOMVs is their lipopolysaccharide (LPS) content, limiting their translatability to the clinic due to potential adverse ef...

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Dades bibliogràfiques
Publicat a:Mol Ther
Autors principals: Watkins, Hannah C., Rappazzo, C. Garrett, Higgins, Jaclyn S., Sun, Xiangjie, Brock, Nicole, Chau, Annie, Misra, Aditya, Cannizzo, Joseph P.B., King, Michael R., Maines, Taronna R., Leifer, Cynthia A., Whittaker, Gary R., DeLisa, Matthew P., Putnam, David
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2017
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383554/
https://ncbi.nlm.nih.gov/pubmed/28215994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.01.010
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