Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection

Recombinant, Escherichia coli-derived outer membrane vesicles (rOMVs), which display heterologous protein subunits, have potential as a vaccine adjuvant platform. One drawback to rOMVs is their lipopolysaccharide (LPS) content, limiting their translatability to the clinic due to potential adverse ef...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Watkins, Hannah C., Rappazzo, C. Garrett, Higgins, Jaclyn S., Sun, Xiangjie, Brock, Nicole, Chau, Annie, Misra, Aditya, Cannizzo, Joseph P.B., King, Michael R., Maines, Taronna R., Leifer, Cynthia A., Whittaker, Gary R., DeLisa, Matthew P., Putnam, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383554/
https://ncbi.nlm.nih.gov/pubmed/28215994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.01.010
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