Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection

Recombinant, Escherichia coli-derived outer membrane vesicles (rOMVs), which display heterologous protein subunits, have potential as a vaccine adjuvant platform. One drawback to rOMVs is their lipopolysaccharide (LPS) content, limiting their translatability to the clinic due to potential adverse ef...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Watkins, Hannah C., Rappazzo, C. Garrett, Higgins, Jaclyn S., Sun, Xiangjie, Brock, Nicole, Chau, Annie, Misra, Aditya, Cannizzo, Joseph P.B., King, Michael R., Maines, Taronna R., Leifer, Cynthia A., Whittaker, Gary R., DeLisa, Matthew P., Putnam, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383554/
https://ncbi.nlm.nih.gov/pubmed/28215994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.01.010
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