Outer membrane vesicles displaying engineered glycotopes elicit protective antibodies

The O-antigen polysaccharide (O-PS) component of lipopolysaccharides on the surface of gram-negative bacteria is both a virulence factor and a B-cell antigen. Antibodies elicited by O-PS often confer protection against infection; therefore, O-PS glycoconjugate vaccines have proven useful against a n...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Chen, Linxiao, Valentine, Jenny L., Huang, Chung-Jr, Endicott, Christine E., Moeller, Tyler D., Rasmussen, Jed A., Fletcher, Joshua R., Boll, Joseph M., Rosenthal, Joseph A., Dobruchowska, Justyna, Wang, Zhirui, Heiss, Christian, Azadi, Parastoo, Putnam, David, Trent, M. Stephen, Jones, Bradley D., DeLisa, Matthew P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2016
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932928/
https://ncbi.nlm.nih.gov/pubmed/27274048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518311113
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