Soluble epoxide hydrolase inhibitor attenuates lipopolysaccharide-induced acute lung injury and improves survival in mice

Acute lung injury (ALI) is characterized by rapid alveolar injury, vascular leakage, lung inflammation, neutrophil accumulation, and induced cytokines production leading to lung edema. The mortality rate of patients suffering from ALI remains high. Epoxyeicosatrienoic acids (EETs) are cytochrome P45...

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Veröffentlicht in:Shock
Hauptverfasser: Zhou, Yong, Liu, Tian, Duan, Jia-Xi, Li, Ping, Sun, Guo-Ying, Liu, Yong-Ping, Zhang, Jun, Dong, Liang, Lee, Kin Sing Stephen, Hammcok, Bruce D., Jiang, Jian-Xin, Guan, Cha-Xiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382142/
https://ncbi.nlm.nih.gov/pubmed/27753791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000767
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