Soluble epoxide hydrolase inhibitor attenuates lipopolysaccharide-induced acute lung injury and improves survival in mice

Acute lung injury (ALI) is characterized by rapid alveolar injury, vascular leakage, lung inflammation, neutrophil accumulation, and induced cytokines production leading to lung edema. The mortality rate of patients suffering from ALI remains high. Epoxyeicosatrienoic acids (EETs) are cytochrome P45...

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Publicado no:Shock
Main Authors: Zhou, Yong, Liu, Tian, Duan, Jia-Xi, Li, Ping, Sun, Guo-Ying, Liu, Yong-Ping, Zhang, Jun, Dong, Liang, Lee, Kin Sing Stephen, Hammcok, Bruce D., Jiang, Jian-Xin, Guan, Cha-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382142/
https://ncbi.nlm.nih.gov/pubmed/27753791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000767
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