Identification of potent inhibitors of the chicken soluble epoxide hydrolase

In vertebrates, soluble epoxide hydrolase (sEH) hydrolyzes natural epoxy-fatty acids (EpFAs), which are chemical mediators modulating inflammation, pain, and angiogenesis. Chick embryos are used to study angiogenesis, particularly its role in cardiovascular biology and pathology. To find potent and...

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Bibliographic Details
Published in:Bioorg Med Chem Lett
Main Authors: Shihadih, Diyala S., Harris, Todd R., Yang, Jun, Merzlikin, Oleg, Lee, Kin Sing S., Hammock, Bruce D., Morisseau, Christophe
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277729/
https://ncbi.nlm.nih.gov/pubmed/25479771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.11.053
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