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Identification of potent inhibitors of the chicken soluble epoxide hydrolase

In vertebrates, soluble epoxide hydrolase (sEH) hydrolyzes natural epoxy-fatty acids (EpFAs), which are chemical mediators modulating inflammation, pain, and angiogenesis. Chick embryos are used to study angiogenesis, particularly its role in cardiovascular biology and pathology. To find potent and...

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Bibliografische gegevens
Gepubliceerd in:Bioorg Med Chem Lett
Hoofdauteurs: Shihadih, Diyala S., Harris, Todd R., Yang, Jun, Merzlikin, Oleg, Lee, Kin Sing S., Hammock, Bruce D., Morisseau, Christophe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277729/
https://ncbi.nlm.nih.gov/pubmed/25479771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.11.053
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