Analysis of origin and protein-protein interaction maps suggests distinct oncogenic role of nuclear EGFR during cancer evolution

Receptor tyrosine kinase EGFR usually is localized on plasma membrane to induce progression of many cancers including cancers in children (Bodey et al. In Vivo. 2005, 19:931-41), but it contains a nuclear localization signal (NLS) that mediates EGFR nuclear translocation (Lin et al. Nat Cell Biol. 2...

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Bibliografiska uppgifter
I publikationen:J Cancer
Huvudupphovsmän: Sharip, Ainur, Abdukhakimova, Diyora, Wang, Xiao, Kim, Alexey, Kim, Yevgeniy, Sharip, Aigul, Orakov, Askarbek, Miao, Lixia, Sun, Qinglei, Chen, Yue, Chen, Zhenbang, Xie, Yingqiu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ivyspring International Publisher 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381180/
https://ncbi.nlm.nih.gov/pubmed/28382154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.17961
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