Analysis of origin and protein-protein interaction maps suggests distinct oncogenic role of nuclear EGFR during cancer evolution

Receptor tyrosine kinase EGFR usually is localized on plasma membrane to induce progression of many cancers including cancers in children (Bodey et al. In Vivo. 2005, 19:931-41), but it contains a nuclear localization signal (NLS) that mediates EGFR nuclear translocation (Lin et al. Nat Cell Biol. 2...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Sharip, Ainur, Abdukhakimova, Diyora, Wang, Xiao, Kim, Alexey, Kim, Yevgeniy, Sharip, Aigul, Orakov, Askarbek, Miao, Lixia, Sun, Qinglei, Chen, Yue, Chen, Zhenbang, Xie, Yingqiu
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381180/
https://ncbi.nlm.nih.gov/pubmed/28382154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.17961
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