Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma

Systemic sclerosis (SSc), or scleroderma, is a multisystem autoimmune disorder characterized by vasculopathy and fibrosis in the skin and internal organs, most frequently in the esophagus and lungs. Hitherto, studies on SSc pathogenesis centered on immune cells, vascular cells, and fibroblasts. Alth...

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Bibliografiska uppgifter
I publikationen:J Exp Med
Huvudupphovsmän: Takahashi, Takehiro, Asano, Yoshihide, Sugawara, Koji, Yamashita, Takashi, Nakamura, Kouki, Saigusa, Ryosuke, Ichimura, Yohei, Toyama, Tetsuo, Taniguchi, Takashi, Akamata, Kaname, Noda, Shinji, Yoshizaki, Ayumi, Tsuruta, Daisuke, Trojanowska, Maria, Sato, Shinichi
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2017
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379967/
https://ncbi.nlm.nih.gov/pubmed/28232470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160247
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