Bosentan reverses the pro-fibrotic phenotype of systemic sclerosis dermal fibroblasts via increasing DNA binding ability of transcription factor Fli1

Por Akamata, Kaname, Asano, Yoshihide, Aozasa, Naohiko, Noda, Shinji, Taniguchi, Takashi, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Sato, Shinichi
Publicado em 2014

Fibrosis, Vascular Activation, and Immune Abnormalities Resembling Systemic Sclerosis in Bleomycin-Treated Fli-1–Haploinsufficient Mice

Por Taniguchi, Takashi, Asano, Yoshihide, Akamata, Kaname, Noda, Shinji, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Trojanowska, Maria, Sato, Shinichi
Publicado no Arthritis Rheumatol (2015)

Endothelin Receptor Blockade Ameliorates Vascular Fragility in Endothelial Cell–Specific Fli-1–Knockout Mice by Increasing Fli-1 DNA Binding Ability

Por Akamata, Kaname, Asano, Yoshihide, Yamashita, Takashi, Noda, Shinji, Taniguchi, Takashi, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Trojanowska, Maria, Sato, Shinichi
Publicado no Arthritis Rheumatol (2015)

Therapeutic targeting of TAZ and YAP by dimethyl fumarate in systemic sclerosis fibrosis

Por Toyama, Tetsuo, Looney, Agnieszka P., Baker, Brendon M., Stawski, Lukasz, Haines, Paul, Simms, Robert, Szymaniak, Aleksander D., Varelas, Xaralabos, Trojanowska, Maria
Publicado no J Invest Dermatol (2017)

Multifaceted contribution of the TLR4-activated IRF5 transcription factor in systemic sclerosis

Por Saigusa, Ryosuke, Asano, Yoshihide, Taniguchi, Takashi, Yamashita, Takashi, Ichimura, Yohei, Takahashi, Takehiro, Toyama, Tetsuo, Yoshizaki, Ayumi, Sugawara, Koji, Tsuruta, Daisuke, Taniguchi, Tadatsugu, Sato, Shinichi
Publicado no Proc Natl Acad Sci U S A (2015)

Glycyrrhizin Ameliorates Fibrosis, Vasculopathy, and Inflammation in Animal Models of Systemic Sclerosis

Por Yamashita, Takashi, Asano, Yoshihide, Taniguchi, Takashi, Nakamura, Kouki, Saigusa, Ryosuke, Miura, Shunsuke, Toyama, Tetsuo, Takahashi, Takehiro, Ichimura, Yohei, Yoshizaki, Ayumi, Trojanowska, Maria, Sato, Shinichi
Publicado no J Invest Dermatol (2016)

A Possible Contribution of Altered Cathepsin B Expression to the Development of Skin Sclerosis and Vasculopathy in Systemic Sclerosis

Por Noda, Shinji, Asano, Yoshihide, Akamata, Kaname, Aozasa, Naohiko, Taniguchi, Takashi, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Sumida, Hayakazu, Yanaba, Koichi, Tada, Yayoi, Sugaya, Makoto, Kadono, Takafumi, Sato, Shinichi
Publicado em 2012

Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma

Por Takahashi, Takehiro, Asano, Yoshihide, Sugawara, Koji, Yamashita, Takashi, Nakamura, Kouki, Saigusa, Ryosuke, Ichimura, Yohei, Toyama, Tetsuo, Taniguchi, Takashi, Akamata, Kaname, Noda, Shinji, Yoshizaki, Ayumi, Tsuruta, Daisuke, Trojanowska, Maria, Sato, Shinichi
Publicado no J Exp Med (2017)

Simultaneous downregulation of KLF5 and Fli1 is a key feature underlying systemic sclerosis

Por Noda, Shinji, Asano, Yoshihide, Nishimura, Satoshi, Taniguchi, Takashi, Fujiu, Katsuhito, Manabe, Ichiro, Nakamura, Kouki, Yamashita, Takashi, Saigusa, Ryosuke, Akamata, Kaname, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Tsuruta, Daisuke, Trojanowska, Maria, Nagai, Ryozo, Sato, Shinichi
Publicado no Nat Commun (2014)