A Possible Contribution of Altered Cathepsin B Expression to the Development of Skin Sclerosis and Vasculopathy in Systemic Sclerosis

Cathepsin B (CTSB) is a proteolytic enzyme potentially modulating angiogenic processes and extracellular matrix remodeling. While matrix metalloproteinases are shown to be implicated in tissue fibrosis and vasculopathy associated with systemic sclerosis (SSc), the role of cathepsins in this disease...

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מידע ביבליוגרפי
Main Authors: Noda, Shinji, Asano, Yoshihide, Akamata, Kaname, Aozasa, Naohiko, Taniguchi, Takashi, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Sumida, Hayakazu, Yanaba, Koichi, Tada, Yayoi, Sugaya, Makoto, Kadono, Takafumi, Sato, Shinichi
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285678/
https://ncbi.nlm.nih.gov/pubmed/22384200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032272
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