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Fibrosis, Vascular Activation, and Immune Abnormalities Resembling Systemic Sclerosis in Bleomycin-Treated Fli-1–Haploinsufficient Mice

OBJECTIVE: Fli-1, a potential predisposing factor for systemic sclerosis (SSc), is constitutively down-regulated in the lesional skin of patients with SSc by an epigenetic mechanism. To investigate the impact of Fli-1 deficiency on the induction of an SSc phenotype in various cell types, we generate...

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Bibliografski detalji
Izdano u:Arthritis Rheumatol
Glavni autori: Taniguchi, Takashi, Asano, Yoshihide, Akamata, Kaname, Noda, Shinji, Takahashi, Takehiro, Ichimura, Yohei, Toyama, Tetsuo, Trojanowska, Maria, Sato, Shinichi
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342755/
https://ncbi.nlm.nih.gov/pubmed/25385187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38948
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