Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma

Systemic sclerosis (SSc), or scleroderma, is a multisystem autoimmune disorder characterized by vasculopathy and fibrosis in the skin and internal organs, most frequently in the esophagus and lungs. Hitherto, studies on SSc pathogenesis centered on immune cells, vascular cells, and fibroblasts. Alth...

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Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Takahashi, Takehiro, Asano, Yoshihide, Sugawara, Koji, Yamashita, Takashi, Nakamura, Kouki, Saigusa, Ryosuke, Ichimura, Yohei, Toyama, Tetsuo, Taniguchi, Takashi, Akamata, Kaname, Noda, Shinji, Yoshizaki, Ayumi, Tsuruta, Daisuke, Trojanowska, Maria, Sato, Shinichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2017
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379967/
https://ncbi.nlm.nih.gov/pubmed/28232470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160247
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