Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study

Gelatinase B or matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) is increased in inflammatory processes and cancer, and is associated with disease progression. In part, this is due to MMP-9-mediated degradation of extracellular matrix, facilitating influx of leukocytes into inflamed tissues and inv...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vandooren, Jennifer, Knoops, Sofie, Aldinucci Buzzo, João L., Boon, Lise, Martens, Erik, Opdenakker, Ghislain, Kolaczkowska, Elzbieta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378356/
https://ncbi.nlm.nih.gov/pubmed/28369077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174853
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