Endotoxemia shifts neutrophils with TIMP-free gelatinase B/MMP-9 from bone marrow to the periphery and induces systematic upregulation of TIMP-1

Lipopolysaccharides or endotoxins elicit an excessive host inflammatory response and lead to life-threatening conditions such as endotoxemia and septic shock. Lipopolysaccharides trigger mobilization and stimulation of leukocytes and exaggerated production of pro-inflammatory molecules including cyt...

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Publicado no:Haematologica
Main Authors: Vandooren, Jennifer, Swinnen, Wannes, Ugarte-Berzal, Estefania, Boon, Lise, Dorst, Daphne, Martens, Erik, Opdenakker, Ghislain
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622851/
https://ncbi.nlm.nih.gov/pubmed/28775117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.168799
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