MMP-9/Gelatinase B Degrades Immune Complexes in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is a common and devastating autoimmune disease, characterized by a dysregulated adaptive immune response against intracellular antigens, which involves both autoreactive T and B cells. In SLE, mainly intracellular autoantigens generate autoantibodies and these asse...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ugarte-Berzal, Estefania, Boon, Lise, Martens, Erik, Rybakin, Vasily, Blockmans, Daniel, Vandooren, Jennifer, Proost, Paul, Opdenakker, Ghislain
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440319/
https://ncbi.nlm.nih.gov/pubmed/30967870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00538
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