Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation

Patterns of gene expression in tumors can arise as a consequence of or result in genomic instability, characterized by the accumulation of somatic copy number alterations (SCNAs) and point mutations (PMs). Expression signatures have been widely used as markers for genomic instability, and both SCNAs...

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Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Buccitelli, Christopher, Salgueiro, Lorena, Rowald, Konstantina, Sotillo, Rocio, Mardin, Balca R., Korbel, Jan O.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378169/
https://ncbi.nlm.nih.gov/pubmed/28320919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.212225.116
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