Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation

Patterns of gene expression in tumors can arise as a consequence of or result in genomic instability, characterized by the accumulation of somatic copy number alterations (SCNAs) and point mutations (PMs). Expression signatures have been widely used as markers for genomic instability, and both SCNAs...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Res
Prif Awduron: Buccitelli, Christopher, Salgueiro, Lorena, Rowald, Konstantina, Sotillo, Rocio, Mardin, Balca R., Korbel, Jan O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378169/
https://ncbi.nlm.nih.gov/pubmed/28320919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.212225.116
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