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Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation
Patterns of gene expression in tumors can arise as a consequence of or result in genomic instability, characterized by the accumulation of somatic copy number alterations (SCNAs) and point mutations (PMs). Expression signatures have been widely used as markers for genomic instability, and both SCNAs...
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| 發表在: | Genome Res |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5378169/ https://ncbi.nlm.nih.gov/pubmed/28320919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.212225.116 |
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