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Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation

Patterns of gene expression in tumors can arise as a consequence of or result in genomic instability, characterized by the accumulation of somatic copy number alterations (SCNAs) and point mutations (PMs). Expression signatures have been widely used as markers for genomic instability, and both SCNAs...

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Detaylı Bibliyografya
Yayımlandı:Genome Res
Asıl Yazarlar: Buccitelli, Christopher, Salgueiro, Lorena, Rowald, Konstantina, Sotillo, Rocio, Mardin, Balca R., Korbel, Jan O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378169/
https://ncbi.nlm.nih.gov/pubmed/28320919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.212225.116
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