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Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation

Patterns of gene expression in tumors can arise as a consequence of or result in genomic instability, characterized by the accumulation of somatic copy number alterations (SCNAs) and point mutations (PMs). Expression signatures have been widely used as markers for genomic instability, and both SCNAs...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Buccitelli, Christopher, Salgueiro, Lorena, Rowald, Konstantina, Sotillo, Rocio, Mardin, Balca R., Korbel, Jan O.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378169/
https://ncbi.nlm.nih.gov/pubmed/28320919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.212225.116
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