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Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation
Patterns of gene expression in tumors can arise as a consequence of or result in genomic instability, characterized by the accumulation of somatic copy number alterations (SCNAs) and point mutations (PMs). Expression signatures have been widely used as markers for genomic instability, and both SCNAs...
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Publicado no: | Genome Res |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5378169/ https://ncbi.nlm.nih.gov/pubmed/28320919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.212225.116 |
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