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Role of malate dehydrogenase in facilitating lactate dehydrogenase to support the glycolysis pathway in tumors
High aerobic glycolysis, as one of the hallmarks of cancer cells, requires nicotinamide adenine dinucleotide (NAD(+)) as a vital co-factor, to guarantee the flow of glycolysis. Malate dehydrogenase (MDH), as an important enzyme in cancer metabolism, is a source of NAD(+) additional to lactate dehydr...
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| Publicado no: | Biomed Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374908/ https://ncbi.nlm.nih.gov/pubmed/28413646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2017.873 |
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