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Role of malate dehydrogenase in facilitating lactate dehydrogenase to support the glycolysis pathway in tumors
High aerobic glycolysis, as one of the hallmarks of cancer cells, requires nicotinamide adenine dinucleotide (NAD(+)) as a vital co-factor, to guarantee the flow of glycolysis. Malate dehydrogenase (MDH), as an important enzyme in cancer metabolism, is a source of NAD(+) additional to lactate dehydr...
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| Publicat a: | Biomed Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
D.A. Spandidos
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374908/ https://ncbi.nlm.nih.gov/pubmed/28413646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2017.873 |
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