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Gradual neofunctionalization in the convergent evolution of trichomonad lactate and malate dehydrogenases

Lactate and malate dehydrogenases (LDH and MDH) are homologous, core metabolic enzymes common to nearly all living organisms. LDHs have evolved convergently from MDHs at least four times, achieving altered substrate specificity by a different mechanism each time. For instance, the LDH of anaerobic t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Protein Sci
Egile Nagusiak: Steindel, Phillip A., Chen, Emily H., Wirth, Jacob D., Theobald, Douglas L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918429/
https://ncbi.nlm.nih.gov/pubmed/26889885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2904
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