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Gradual neofunctionalization in the convergent evolution of trichomonad lactate and malate dehydrogenases
Lactate and malate dehydrogenases (LDH and MDH) are homologous, core metabolic enzymes common to nearly all living organisms. LDHs have evolved convergently from MDHs at least four times, achieving altered substrate specificity by a different mechanism each time. For instance, the LDH of anaerobic t...
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| Publicado no: | Protein Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918429/ https://ncbi.nlm.nih.gov/pubmed/26889885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2904 |
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