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Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer
Increased glucose consumption is a hallmark of cancer cells. The increased consumption and subsequent metabolism of glucose during proliferation creates the need for a constant supply of NAD, a co-factor in glycolysis. Regeneration of the NAD required to support enhanced glycolysis has been attribut...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501748/ https://ncbi.nlm.nih.gov/pubmed/28263970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.36 |
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