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In Search of Small Molecule Inhibitors Targeting the Flexible CK2 Subunit Interface
Protein kinase CK2 is a tetrameric holoenzyme composed of two catalytic (α and/or α’) subunits and two regulatory (β) subunits. Crystallographic data paired with fluorescence imaging techniques have suggested that the formation of the CK2 holoenzyme complex within cells is a dynamic process. Althoug...
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| Publié dans: | Pharmaceuticals (Basel) |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374420/ https://ncbi.nlm.nih.gov/pubmed/28165359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10010016 |
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