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A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies
A small number of proteins form a conserved pathway of centriole duplication. In humans and flies, the binding of PLK4/Sak to STIL/Ana2 initiates daughter centriole assembly. In humans, this interaction is mediated by an interaction between the Polo-Box-3 (PB3) domain of PLK4 and the coiled-coil dom...
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| Publicado no: | Biol Open |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5374404/ https://ncbi.nlm.nih.gov/pubmed/28202467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.024661 |
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